Project:

Therapeutic opportunities of non-invasive neuromodulation after acquired brain injury

Mentor (Advisor):

prof. MUDr. Marcela Grünerová Lippertová, Ph.D.

Department:

Klinika rehabilitačního lékařství FNKV 3LF UK

Contact information:

Šrobárova 50, 100 00 Praha 10

tel. +420 2 67162480

fax +420 2 67163214

e-mail: marcela.grunerova-lippertova@fnkv.cz

Project Narrative:

Among the non-invasive neuromodulation options available today is transcranial direct current stimulation (tDCS). Currently, this method is considered a promising option for influencing brain activity, applicable to the study of cortical representation of sensorimotor, cognitive and other functions, with significant potential for positive therapeutic impact on various forms of neurological and psychological disorders. The use of tDCS is constantly expanding, with psychiatric diagnoses such as depression and schizophrenia being among the most common indications currently used, as well as tDCS being used in the treatment of neuropathic pain and to improve motor and cognitive function after acquired brain injury. The aim of the planned project is to assess the effect of transcranial direct current stimulation on the outcome of standard rehabilitation in patients with impaired upper limb motor function after a stroke. The effect of added neuromodulation using tDCS on improving the outcome of gross and fine motor rehabilitation, which is performed to restore functional ability to manipulate (operate) various surrounding objects, will be investigated. We expect that the neuroplastic changes induced by tDCS will help to enhance the motor learning effect and, as a result, facilitate the performance of functional motor operations controlled by the motor cortex.

Requirements for student applicants:

Completed Master's degree in medicine, physiotherapy or occupational therapy.

Interest in neurorehabilitation.