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Recommended textbooks:

1. Recommended textbook:

Pharmacology - H. P. Rang, et al. - 8th ed. - Elsevier Churchill Livingstone, 2015 (or  7th ed.)

or (alternatively)

Basic & clinical pharmacology - B. G. Katzung - 13th ed. - Lange Medi. Books - McGraw-Hill 2015 (or 12th ed. )


2. Additional texts convenient for a suplementary reading:

Pharmacology (Lippincott's Illustrated Reviews). 6th ed. Wolters Kluver/Lippincott , 2015 (or  5th ed.)

Principles of Pharmacology (The Pathophysiological Basis of Drug Therapy) Golan D.E. et al. , Wolters Kluver/Lippincott , 2012

Pharmacology An Illustrated Review  Simmons M.A., Thieme, 2012

Medical Pharmacology at a Glance - M. J. Neal. 8th ed. Wiley-Blackwell, 2015 (or 7th ed.)

British National Formulary No.70[or higher] - BMJ Books, September 2015 [or more recent editions].


Databases & computers for the students


Methods of evaluation

Conditions for credits & examination

  • A condition for a successful passing the subject "General Pharmacology" is to meet criteria of a Final test from general pharmacology.

     A prerequisite for writing the final test is obtaining a credit from general pharmacology. The credit is obtained after  at least 80% attendance of practicals and meeting criteria of four interim tests (Tests for credits) during the course of General pharmacology :

    1st TEST for credit - PHARMACODYNAMICS I  (Pharmacology of autonomic nervous systém) - Teaching Unit (TU) 3, 5,6,8)- 5th week of the semester

    2nd TEST for credit - PHARMACOKINETICS (basic principles, biotransformation and elimination of DRUGS, TU drugs TU 1,4,7,10)  - 7th week of the semester

    3rd  TEST for credit PHARMACODYNAMICS II ( pharmacology of selected receptors, ion channels, enzymes and regulatory systems - TU 9, 11-16, 18)- 11th week of the semester

    4th TEST fro credit - DRUG PRESCRIPTION - 13th week of the semester


     The tests for credits will be multiple-choice, will be written during practicals in semester weeks given above.



    Examination will be in a form of final multiple-choice test

    Terms of exam (Final tests):

                               Jan 25, 2018 - 10:00-11:30

                               Feb 1, 2018 - 10:00-11:30

                               Feb 8, 2018 - 10:00-11:30


    Capacity: 120 students per term, Final tests will be written in the Burian lecture halls (Ruská 87, Prague 10)


    The questions of the final test will be mainly based on topics in seminars and lectures:


    Basic terminology in pharmacology

    Principles of pharmacokinetics

    Autonomic pharmacology - sympathetic system.

    Autonomic pharmacology - parasympathetic system.

    Biotransformation and elimination of drugs, drug interactions.

    Drugs acting via dopamine, serotonin, histamine

    Drugs acting by inhibition of enzymes

    Drugs acting via ion channels and transporters

    Principles of pharmacologic blood pressure control

    Drug and remedy addiction

    Biological therapy, gene therapy, pharmacogenetics

    Drug discovery and development. Preclinical and clinical trials. EBM.  Placebo.

    Adverse drug reactions. Regulatory agencies (EMA etc). Pharmacovigilance. Pharmacoeconomics.

    Complementary and Alternative Medicine (CAM), homeopathy

    Principles of toxikology - intoxications, termination of drug effect. 

    In case of failure in the final test, a student will have a possibility of another test (2nd test). In case of failure in the 2nd test, a 3rd test will be possible as the last chance.

  • List of important drugs

General Pharmacology - lectures & seminars


Following modules