1. Recommended textbook:
Pharmacology - H. P. Rang, et al. - 8th ed. - Elsevier Churchill Livingstone, 2015 (or 7th ed.)
Basic & clinical pharmacology - B. G. Katzung - 13th ed. - Lange Medi. Books - McGraw-Hill 2015 (or 12th ed. )
2. Additional texts convenient for a suplementary reading:
Pharmacology (Lippincott's Illustrated Reviews). 6th ed. Wolters Kluver/Lippincott , 2015 (or 5th ed.)
Principles of Pharmacology (The Pathophysiological Basis of Drug Therapy) Golan D.E. et al. , Wolters Kluver/Lippincott , 2012
Pharmacology An Illustrated Review Simmons M.A., Thieme, 2012
Medical Pharmacology at a Glance - M. J. Neal. 8th ed. Wiley-Blackwell, 2015 (or 7th ed.)
British National Formulary No.70[or higher] - BMJ Books, September 2015 [or more recent editions].
Methods of evaluation
Conditions for credits & examination
A condition for a successful passing the subject "General Pharmacology" is to meet criteria of a Final test from general pharmacology.
A prerequisite for writing the final test is obtaining a credit from general pharmacology. The credit is obtained after at least 80% attendance of practicals and meeting criteria of four interim tests (Tests for credits) during the course of General pharmacology :
1st TEST for credit - PHARMACODYNAMICS I (Pharmacology of autonomic nervous systém) - Teaching Unit (TU) 3, 5,6,8)- 5th week of the semester
2nd TEST for credit - PHARMACOKINETICS (basic principles, biotransformation and elimination of DRUGS, TU drugs TU 1,4,7,10) - 7th week of the semester
3rd TEST for credit PHARMACODYNAMICS II ( pharmacology of selected receptors, ion channels, enzymes and regulatory systems - TU 9, 11-16, 18)- 11th week of the semester
4th TEST fro credit - DRUG PRESCRIPTION - 13th week of the semester
The tests for credits will be multiple-choice, will be written during practicals in semester weeks given above.
Examination will be in a form of final multiple-choice test
Terms of exam (Final tests):
Jan 25, 2018 - 10:00-11:30
Feb 1, 2018 - 10:00-11:30
Feb 8, 2018 - 10:00-11:30
Capacity: 120 students per term, Final tests will be written in the Burian lecture halls (Ruská 87, Prague 10)
The questions of the final test will be mainly based on topics in seminars and lectures:
Basic terminology in pharmacology
Principles of pharmacokinetics
Autonomic pharmacology - sympathetic system.
Autonomic pharmacology - parasympathetic system.
Biotransformation and elimination of drugs, drug interactions.
Drugs acting via dopamine, serotonin, histamineDrugs acting by inhibition of enzymes
Drugs acting via ion channels and transporters
Principles of pharmacologic blood pressure control
Drug and remedy addiction
Biological therapy, gene therapy, pharmacogenetics
Drug discovery and development. Preclinical and clinical trials. EBM. Placebo.
Adverse drug reactions. Regulatory agencies (EMA etc). Pharmacovigilance. Pharmacoeconomics.
Complementary and Alternative Medicine (CAM), homeopathy
Principles of toxikology - intoxications, termination of drug effect.
In case of failure in the final test, a student will have a possibility of another test (2nd test). In case of failure in the 2nd test, a 3rd test will be possible as the last chance.
- List of important drugs
General Pharmacology - lectures & seminars