MUDr. Jan Hrudka, Ph.D.












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            Department of Pathology 3FM CU and UHKV
            https://www.lf3.cuni.cz/3LF-409.html [ URL "https://www.lf3.cuni.cz/3LF-409.html"]


            Topic title
            The prognostic predictive markers in penile carcinoma: a molecular and morphological study
            Rare subtypes of pancreatic carcinoma: genomic and proteomic prognostic markers.

            Cholangiocarcinoma: immunohistochemistical markers of peripheral and hilar subtype, link t
            predictive markers.





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            * Description of scientific activity
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            Jan Hrudka graduated at Third Faculty of Medicine, Charles University in Prague in 2011. H
            diagnostic pathologist. From 2011 to 2014, he worked at Institute of Pathology, Klinikum F
            From 2014 until today, he works at Institute of Pathology at Third Faculty of Medicine, Ch

            and University Hospital Královské Vinohrady as pathologist, teacher and research worker.

            The main research topic is morphological and molecular pathology of gastrointestinal and u

            in terms of immunohistochemical and molecular methods to identify prognostic and predictiv
            pancreatic, biliary, colorectal, and penile carcinoma.


            PhD student may participate on some of ongoing researchs, including research focused on pe
            with specific financial support from Czech Health Research Council.




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            * Selected publications
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            Hrudka J, Fišerová H, Jelínková K, Matěj R, Waldauf P. Cytokeratin 7 expression as a predi

            an unfavorable prognosis in colorectal carcinoma. Sci Rep. 2021 Sep 9;11(1):17863. doi: 10
            s41598-021-97480-4.


            Hrudka J, Prouzová Z, Mydlíková K, Jedličková K, Holešta M, Whitley A, Havlůj L. FOXF1 as 
            Immunohistochemical Marker of Hilar Cholangiocarcinoma or Metastatic Pancreatic Ductal Ade
            Single Institution Experience. Pathol Oncol Res. 2021 Apr 20;27:1609756. doi: 10.3389/pore


            Hrudka J, Lawrie K, Waldauf P, Ciprová V, Moravcová J, Matěj R. Negative prognostic impact
            expression in tumor cells of undifferentiated (anaplastic) carcinoma with osteoclast-like 

            of the pancreas: study of 13 cases comparing ductal pancreatic carcinoma and review of the
            Virchows Arch. 2020 Nov;477(5):687-696. doi: 10.1007/s00428-020-02830-8.




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            * Selected or ongoing grants/clinical studies
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            Czech Health Research Council: The prognostic predictive markers in penile carcinoma: a mo

            morphological study. NU21J-03-00019