doc. MUDr. Jan Gojda, Ph.D. ****************************************************************************************** * ******************************************************************************************
Department of Internal Medicine 3FM CU and UHKV https://www.lf3.cuni.cz/3LFEN-381.html [ URL "https://www.lf3.cuni.cz/3LFEN-381.html"] https://www.fnkv.cz/diabetologicke-centrum-vedecke-aktivity.php [ URL "https://www.fnkv.cz centrum-vedecke-aktivity.php"] Topic title Intestinal microbiome and metabolome as the link between diet and metabolic profile. Metabolic flexibility: response predictors to diet/exercise intervention Metabolic bone disease in patients on home parenteral nutrition *========================================================================================= * Description of scientific activity *========================================================================================= Clinical Research Unit (CRU) is a joint facility of Department of Internal Medicine and th Research on Nutrition, Metabolism and Diabetes of the Third Medical Faculty of Charles Uni University Hospital Královské Vinohrady. The CRU specializes in a wide range of functional testing, both for clinical and experimental purposes. The unit hosts both the academic and research. The CRU associates directly to the other laboratories of the Center as well as D of the hospital and provides clinical and clinical - experimental services. It integrates theoretical laboratories and translates it to clinical and applied research. Basic methods performed at CRU include functional tests (methods of insulin secretion and insulin sensit studies, dynamic endocrinological tests), calorimetry and exercise tests, fat and muscle t microdialysis. CRU also provides recruitment of volunteers for studies, administration, ba management and data and sample retention, statistical processing, and support for publicat scientific focus is on physiological models in insulin resistance/secretion in cancer host nutrition and diet-derived biocompounds on metabolic health. *========================================================================================= * Selected publications *========================================================================================= Gojda J, Rossmeislová L, Straková R, Tůmová J, Elkalaf M, Jaček M, Tůma P, Potočková J, Kr P, Trnka J, Štich V, Anděl M. Chronic dietary exposure to branched chain amino acids impai disposal in vegans but not in omnivores. Eur. J. Clin. Nutr. 2017. doi:10.1038/ejcn.2016.2 Gojda J, Waldauf P, Hrušková N, Blahutová B, Krajčová A, Urban T, et al. (2019) Lactate pr without hypoxia in skeletal muscle during electrical cycling: Crossover study of femoral v differences in healthy volunteers. PLoS ONE 14(3): e0200228. https://doi.org/10.1371/journ Gojda, J.; Cahova, M. Gut Microbiota as the Link between Elevated BCAA Serum Levels and In Biomolecules 2021, 11, 1414. https://doi.org/10.3390/biom11101414 *========================================================================================= * Selected or ongoing grants/clinical studies *========================================================================================= Modification of gut microbiota in the treatment of insulin resistance: a personalized appr (NV18-01-00040 2018 – 2021) Pancreatic Cancer: Metabolic Derangements Associated With Insulin Resistance (19-01-00101 KOMPAS: Cohort prospective study of emerging nutritional factors among families (NU21-09-0 *========================================================================================= * PhD Students *========================================================================================= Number of PhD students currently studying: 4