prof. MUDr. Pavel Kraml, Ph.D. ****************************************************************************************** * ******************************************************************************************
Dept. of Internal Medicine, Third Faculty of Medicine, Charles University Prague and Unive Královské Vinohrady, Prague Center for research of diabetes, metabolism and nutrition Center for diagnosis and treatment of hyperlipoproteinemia https://www.lf3.cuni.cz/3LF-654.html [ URL "https://www.lf3.cuni.cz/3LF-654.html"] Topic title New risk factors of atherosclerosis associated cardiovascular diseases *========================================================================================= * Description of scientific activity *========================================================================================= The scientific activity is focused on the non-traditional risk factors of atherosclerosis inflammation, oncological therapy. *========================================================================================= * Selected publications *========================================================================================= Kraml PJ, Klein RL, Huang Y, Nareika A, Lopes-Virella MF: Iron Loading Enhances LDL Uptake Scavenger Receptor in THP-I Macrophages. Metabolism 2005; 54:453-459 doi: 10.1016/j.metabo Šiklová M, Koc M, Rossmeislová L, Kraml P: Serum oxLDL-?2GPI complex reflects metabolit sy inflammation in adipose tissue in obese. Int J Obes (Lond) 2017; doi 201710.1038/ijo.2017. Riško P, Pláteník J, Buchal R, Potočková J, Kraml PJ: Long-term donors versus non-donor me Iron metabolism and the atherosclerosis process. Atherosclerosis 2018; 272: 14-20. doi: 10 j.atherosclerosis.2018.03.009. Epub 2018 Mar 3. PMID: 29544084. Cepelova M, Kruseova J, Luks A, Capek V, Cepela P, Potockova J, Kraml P. Accelerated ather hyperlipoproteinemia and insulin resistance in long-term survivors of Hodgkin lymphoma dur adolescence. Neoplasma. 2019 Jul 12;66(6):978-987. doi: 10.4149/neo_2019_190115N45. *========================================================================================= * Selected or ongoing grants/clinical studies *========================================================================================= 2012 – 2015 IGA MZ ČR NT13671-4/2012: Reactive iron in monocytes and its role in the proce atherogenesis 2015 – 2018 AZV MZČR 15-30494A: Incidence of hyperlipoproteinemia in long-term survivors o lymphoma during childhood and adolescence. 2014 – 2019 Research program PRVOUK 031: Ferritin as a predictor of the cardiovascular and diseases *========================================================================================= * PhD Students *========================================================================================= Number of PhD students currently studying : 1 Number of defended students with year of defence: 2 (2011, 2019)