Presentation of Department ****************************************************************************************** * Recent publications ****************************************************************************************** • Lana D, Branca JJV, Delfino G, Giovannini MG, Casamenti F, Nardiello P, Bucciantini M, S P, Zecchi-Orlandini S, Nosi D. Morphofunctional Investigation in a Transgenic Mouse Mode Disease: Non-Reactive Astrocytes Are Involved in A? Load and Reactive Astrocytes in Plaq Cells. 2023 Sep 12;12(18):2258. doi: 10.3390/cells12182258. • Wurst Z, Birčák Kuchtová B, Křemen J, Lahutsina A, Ibrahim I, Tintěra J, Bartoš A, Brabe Zach P, Musil V, Olympiou N, Mrzílková J. Basal Ganglia Compensatory White Matter Change Alzheimer's Disease. Cells. 2023 Apr 23;12(9):1220. doi: 10.3390/cells12091220. • Lahutsina A, Spaniel F, Mrzilkova J, Morozova A, Brabec M, Musil V, Zach P. Morphology o Cingulate Cortex and Its Relation to Schizophrenia. J Clin Med. 2022 Dec 21;12(1):33. do jcm12010033. • Řasová K, Bučková B, Prokopiusová T, Procházková M, Angel G, Marková M, Hrušková N, Štět Špaňhelová Š, Mareš J, Tintěra J, Zach P, Musil V, Hlinka J. A Three-Arm Parallel-group Trial documents balance improvement without much evidence of white matter integrity chan people with multiple sclerosis following two months ambulatory neuroproprioceptive "faci and inhibition" physical therapy. Eur J Phys Rehabil Med. 2021 Dec;57(6):889-899. doi: 1 S1973-9087.21.06701-0. • Frýdlová P, Mrzílková J, Šeremeta M, Křemen J, Dudák J, Žemlička J, Minnich B, Kverková P, Frynta D. Determinate growth is predominant and likely ancestral in squamate reptiles 2020 Dec 23;287(1941):20202737. doi: 10.1098/rspb.2020.2737. • Sol D, Olkowicz S, Sayol F, Kocourek M, Zhang Y, Marhounová L, Osadnik C, Corssmit E, Ga Martin TE, Lefebvre L, Němec P. Neuron numbers link innovativeness with both absolute an size in birds. Nat Ecol Evol. 2022 Sep;6(9):1381-1389. doi: 10.1038/s41559-022-01815-x. ****************************************************************************************** * Research focus of the department, Ph.D. studies and other activities ****************************************************************************************** • Research focus of the department: Neuroscience (Alzheimer's disease, imaging techniques in neuroscience, Prof. Petr Zach) PGS students: Dr. Tanya Rai - collaborative project with NUDZ, ESO database, morphology of the parafac patients with schizophrenia (OR Neuroscience) Dr. Alexandra Morozova - magnetic resonance imaging of CNS vascular supply, quantificati perivascular spaces (PVS) in patients with Alzheimer's disease (OR Neuroscience) Dr. Nicoletta Olympiou - DTI study of the course and changes of fasciculus arcuatus and in patients with Alzheimer's disease (OR Neuroscience) Dr. Martin Sheremeta - CNS changes in metabolic syndrome in a rabbit MRI model (OR Physi Dr. Paolo Palma - Tracking the progression of schizoaffective disorder: longitudinal ana clinical, behavioral and brain biomarkers (OR Neuroscience) (supervisor Dr. Zaytseva) dr. Zdeněk Wurst - Analysis of memory structure connectivity in different types of CNS p Neuroscience) (supervisor dr. Mrzílková) Physical anthropology (growth of children, growth charts - RNDr. Jitka Riedlová) Experimental imaging of hard and soft tissues on micro-CT (the department is equipped wi Skyscan micro-CT scanner - MUDr. Jana Mrzílková) Research on amyotrophic lateral sclerosis in a transgenic mouse model - RNDr. Zdeněk Mus Evolution of brain complexity and processing capacity in birds - Martin Kocourek, Ph.D. Clinical Anatomy - Prof. MUDr. Václav Báča, Ph.D. • *Article Compensatory shift of white matter parameters of the subcalosal area and parate gyrus on DTI in patients with Alzheimer's disease. Kuchtová B, Wurst Z, Mrzílková J, Ibr Tintěra J, Bartoš A, Musil V, Kieslich K, Zach P. Curr Alzheimer Res. 2018;15(6):590-599 10.2174/1567205015666171227155510. *It was cited in the Correspondence section of the New England Journal of Medicine (IF=7 Region Deep Brain Stimulation-Induced Memory Flashbacks in Alzheimer's Disease. N Engl J 381:783-785. DOI: 10.1056/NEJMc1905240. *International collaboration with the University of Florence - Dipartimento di Medicina e Clinica (DMSC), prof. Annamaria Morelli (metabolic rabbit syndrome, neurohistology of and MRI of the rabbit brain in collaboration with IKEM, Assoc. ing. Daniel Jirák), prof. (role of astroglia in a transgenic mouse model of Alzheimer's disease), Dr. Daniele Lana Neuropharmacology, UNIFi) (neuroimmunohistochemistry in an animal model of Alzheimer's d *International collaboration with the University of Sydney, School of Medical Sciences [ Laboratory of Molecular Neuroscience and Dementia (prof. Damian Holsinger, pharmacologic non-pharmacological interventions that can bring about treatments for Alzheimer's diseas *Collaboration with the Faculty of Philosophy of Charles University: Caenorhabditis eleg influence of Lithium 6 and 7 isotopes on motility - significance for the change of isoto ratio in drugs for bipolar disease (Marie Macůrková, Ph.D.) *Collaboration with NUDZ, Klecany: dr. Filip Španiel, analysis of magnetic resonance ima from ESO and HYDRA database in patients with schizophrenia and Alzheimer's disease, morp focused on the analysis of grey and white matter structure; dr. Karel Valeš: brain energ research on mTOR metabolic pathway, metabolic syndrome in animal model and changes in gr matter of CNS *Interesting article: Sol, D., Olkowicz, S., Sayol, F., Kocourek, M., Zhang, Y., Marhoun Osadnik, C., Corssmit, E., Garcia-Porta, J., Martin, T. E., Lefebvre, L., & Nemec, P. (2 numbers link innovativeness with both absolute and relative brain size in birds. Nature Evolution, 6(9), 1381-1389 *========================================================================================= * Membership - Professional Activities *========================================================================================= Václav Báča, MD., Ph.D., Professor • Czech anatomical society • European Association of Clinical Anatomists • opponent FRVŠ • external opponent in the program EQUAL fonds of European Union • Czech anatomical society • opponent FRVŠ RNDr. Jitka Riedlová • Czech anthropological society Josef Stingl, MD., PhD., Professor • European Association of Clinical Anatomists - vicepresident Petr Zach, MD., PhD., Professor • Neuroscience Society JEP • Mind and Life Institute, Boulder, Colorado, USA • Brain Mapping Project, New York, USA • Neuroscience Society, New York, USA *========================================================================================= * Membership in Editorial Board *========================================================================================= Václav Báča, MD., PhD., Professor • Surgical and Radiologic Anatomy - reviewer Josef Stingl, MD., PhD., Professor • Scripta medica Brno - reviewer • Surgical and Radiologic Anatomy [ URL ""]